United States securities and exchange commission logo June 25, 2024 Jill Broadfoot Chief Financial Officer aTYR PHARMA INC 10240 Sorrento Valley Road Suite 300 San Diego, CA 92014 Re: aTYR PHARMA INC Form 10-K for Fiscal Year Ended December 31, 2023 File No. 001-37378 Dear Jill Broadfoot: We have completed our review of your filings. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Life Sciences